平安！ 发表于 2011-11-9 19:57 ) [" c' Z( e- X7 R: S3 ^4 ~
Pazopanib (100 mg/kg/day free base equivalent)
; b" n6 H7 Q N7 n+ ]2 k8 x 这是个已经在美国上市的老药了，能下载到正式药物使用说明书英文版。
* I0 e( F; ^5 y3 E9 b0 \8 c搜索了一下，原料一大堆。; x* l3 ^) v7 O
& c6 l5 x: g+ K对不起！100mg/kg是用于移植瘤的，我弄错了。/ J( C3 U3 {% I+ s. l/ e& ~0 r
8 R8 k* A, X( m" T# i* m9 z# u以下是正版说明书的推荐用量。
7 q2 U, T4 S& |1 ]
! D. p' _0 _9 [* o$ D) b--------------------- DOSAGE AND ADMINISTRATION ----------------
% I# \$ l9 T0 j1 z* 800 mg orally once daily without food (at least 1 hour before or 2 hours after a meal). (2.1) ; U2 m& b" a7 T; F' j! q3 h
* Baseline moderate hepatic impairment – 200 mg orally once daily. Not recommended in patients with severe hepatic impairment. (2.2) 7 |/ C- y) c# y3 A
---------------------DOSAGE FORMS AND STRENGTHS --------------) Y0 h% L: R- |4 g% ~
200 mg tablets. (3) 1 X2 |$ o9 ~0 v, J. S; t+ Z: u0 ?5 C, }9 W
-------------------------------CONTRAINDICATIONS------------------------ |
显身卡
