看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯，血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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9 G" H) U2 C' j9 U- |( iCurrently available feasibility data for possible combination strategies. 5 t& P1 m; t6 G6 t
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Combination Feasibility according to preliminary data
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/ C) ^, n& }1 j1 r( _, dBevacizumab + sorafenib Yes, reduced dose
: } ]! Y1 k5 s+ ^( Q6 q6 rBevacizumab + sunitinib† No
/ y! O* S3 L; \5 s4 @4 t5 `* e7 H8 pBevacizumab + temsirolimus Yes 8 D& y }3 B$ S8 [2 p2 O3 K
Bevacizumab + everolimus Yes
9 ^1 ~: H5 d/ S9 YSorafenib + sunitinib ? 5 F* ^0 m- j4 n# h, O
Sorafenib + temsirolimus Yes, reduced dose
4 C+ ?* b2 C$ J5 j7 G0 h9 sSorafenib + everolimus Yes, reduced dose - F0 ?! C7 E3 Z2 K# u" x( r
Sunitinib + temsirolimus† No 8 s6 |& e3 p9 [% D5 f X, q1 V0 F
Sunitinib + everolimus ? 0 d0 m8 a# r: H2 B2 g0 k# m
Temsirolimus + everolimus ? 7 J/ C* Y$ r2 A/ _& O% a! [
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†Led to US FDA warning.: o" V* ^; t+ x* f5 {" N+ E
?: As yet unattempted combination.
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