看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。/ X! n- W3 c' M5 H' k! d
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6 D- {: H7 q! w. |1 pCurrently available feasibility data for possible combination strategies.
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6 v y" K: t+ BCombination Feasibility according to preliminary data
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2 Q3 L2 P S/ NBevacizumab + sorafenib Yes, reduced dose
9 I5 y; J' p) _ U( h4 A/ R5 yBevacizumab + sunitinib† No 3 r9 `5 g3 b8 {% n" q e' K! a7 b$ ^
Bevacizumab + temsirolimus Yes
7 v1 H8 ?, ~" BBevacizumab + everolimus Yes
9 _) ^& Z4 X0 sSorafenib + sunitinib ? 7 t! H+ I" S q8 w) P
Sorafenib + temsirolimus Yes, reduced dose . M7 g+ r5 g) X; ^0 n: i3 B# O
Sorafenib + everolimus Yes, reduced dose 1 i5 e# @7 D* O# f" m6 T
Sunitinib + temsirolimus† No / q( F7 J5 Y" \2 M( B8 X6 l
Sunitinib + everolimus ? & B" a5 J! S* { G& @
Temsirolimus + everolimus ? 8 R6 G1 L+ m/ G9 F- L8 e
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†Led to US FDA warning.) p: L0 s7 m: G
?: As yet unattempted combination./ t \6 |. }+ v9 G. V
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